The Program faculty recommend that students in Science Studies, whichever their "home" Department, should have first-hand experience of scientific practice as part of their graduate studies. Internships might include a period of work in a scientific laboratory, a science museum or archive, participation in scientific fieldwork or an expedition, working at a preservation laboratory, hospital, regulatory agency, etc. A report from the internship is part of the basis for grading and evaluation in the program. Program faculty mentors assist students by helping them plan their internships and by using their contacts in scientific departments at UC San Diego or elsewhere. Students are encouraged to contact the program director or relevant faculty for details.

Students who, before enrolling in the Program, have had substantial practical experience in some aspects of scientific work may apply for a waiver of the requirement to undertake an internship, but will still be required to write a report reflecting on that earlier experience.